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Rat interferon enhances the expression of acetycholine receptors in rat myotubes in culture

✍ Scribed by P. André; S. Braun; A. C. Passaquin; G. Coupin; J. Bartholeyns; J. M. Warter; Dr. P. Poindron

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
803 KB
Volume
19
Category
Article
ISSN
0360-4012

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✦ Synopsis

Interferon enhances alpha-bungarotoxin binding on 5-day-old rat myotubes. The increase is time- and dose-dependent. KD for alpha-bungarotoxin remains unchanged in the presence and in the absence of interferon, while the maximum number of binding sites is dramatically affected by interferon. Cycloheximide inhibits the effect of interferon, which suggests that the enhancement of alpha-bungarotoxin binding depends on protein synthesis.

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