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Rat hepatic CYP1A1 and CYP1A2 induction by menadione

✍ Scribed by Y.A. Sidorova; A.Y. Grishanova; V.V. Lyakhovich

Book ID
119378052
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
112 KB
Volume
155
Category
Article
ISSN
0378-4274

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi