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Rat brain concentrations of 5-hydroxytryptamine following acute and chronic administration of MAO-inhibiting antidepressants

โœ Scribed by Baker, Glen B.; LeGatt, Donald F.; Coutts, Ronald T.; Dewhurst, William G.


Book ID
122869479
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
281 KB
Volume
8
Category
Article
ISSN
0278-5846

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Because tricyclic antidepressants (TAD) are usually given chronically to patients, both their acute and their chronic effects on 5-hydroxytryptamine (5-HT) metabolism were studied. The probenecid method was used and, in addition to 5-hydroxy-indoleacetic acid (5-HIAA), some other indole compounds in