𝔖 Bobbio Scriptorium
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Ras Proteins Mediate Induction of Uncoupling Protein, IGF-I, and IGF-I Receptor in Rat Fetal Brown Adipocyte Cell Lines

✍ Scribed by PORRAS, ALMUDENA; HERNÁNDEZ, ELEUTERIO R.; BENITO, MANUEL


Book ID
126088049
Publisher
Mary Ann Liebert
Year
1996
Tongue
English
Weight
690 KB
Volume
15
Category
Article
ISSN
1044-5498

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Fetal brown adipocytes expressed uncoupling protein 1 (UCP1) mRNA, this expression being blunted throughout culture for 24 h in a serum-free medium. At physiological doses, either insulin-like growth factor I (IGF-I) or insulin turned out to be as potent as dibutyryl cAMP (dbcAMP) in increasing UCP1