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RAS mutation analysis in a large cohort of Chinese patients with acute myeloid leukemia

✍ Scribed by Yang, Xiaofei; Qian, Jun; Sun, Aining; Lin, Jiang; Xiao, Gaofei; Yin, Jia; Chen, Suning; Wu, Depei

Book ID: 118263592
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 374 KB
Volume: 46
Category: Article
ISSN: 0009-9120
DOI: 10.1016/j.clinbiochem.2012.12.022

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## Abstract N‐ras gene activation occurs via single base substitutions in codons 12, 13, and 61. We have developed a rapid screening method, termed allele specific restriction analysis (ASRA), for detection of N‐ras mutations at these three critical codons in acute myeloid leukemia (AML). Patient D