𝔖 Bobbio Scriptorium
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Ras interference as cancer therapy

✍ Scribed by Anja M Duursma; Reuven Agami


Book ID
114340624
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
168 KB
Volume
13
Category
Article
ISSN
1044-579X

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Given the key role of Ras in the mitogenic signaling by receptor tyrosine kinases, several targets upstream of Ras may prove to be excellent targets for drugs in the treatment of cancer caused by oncogenic tyrosine kinases. CGP78850 is a potent competitor of Grb2 SH2-phosphopeptide interactions. Thi