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Rare involvement of submandibular gland by oral squamous cell carcinoma

✍ Scribed by Tseng-Cheng Chen; Wu-Chia Lo; Jenq-Yuh Ko; Pei-Jen Lou; Tsung-Lin Yang; Cheng-Ping Wang

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
73 KB
Volume
31
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

Background

The true involvement of the submandibular gland in primary oral cancer seems quite uncommon.

Methods

We retrospectively reviewed the pathologic records of 342 patients with oral squamous cell carcinoma who underwent wide excision of primary oral cancer and simultaneous neck dissection from January 2000 to December 2003.

Results

Of the 383 submandibular glands, only 7 (1.8%) exhibited tumor involvement. Of them, 5 glands were involved by direct extension from the primary tumor. One gland showed local invasion from an adjacent involved lymph node in level I and 1 was from intraglandular lymph node metastasis. All of these 6 tumors with submandibular gland involvement were T4 disease (p = .0003) and the neck nodal status on each was more than N2b (p < .0001).

Conclusion

The patients with early‐stage oral squamous cell carcinoma with preoperative N0 neck may be candidates for preservation of the submandibular gland. Β© 2009 Wiley Periodicals, Inc. Head Neck, 2009

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