## BACKGROUND. Brain tumors in patients with Down syndrome (DS) rarely are reported, and their behavior is not well known. ## METHODS. The authors report on a male patient age 19 years who had DS with diffuse astrocytoma (World Health Organization Grade 2) that recurred twice despite treatment,
β¦ LIBER β¦
Rapidly progressive parkinsonism in a self-reported user of Ecstasy and other drugs
β Scribed by Padraig O'Suilleabhain; Cole Giller
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 59 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
A 38βyearβold man developed parkinsonism that progressed to Hoehn and Yahr stage 5 within 4 years of onset. Response to ropinirole deteriorated, levodopa was not tolerated, and subthalamic nucleus stimulation has provided only partial relief of symptoms. He reported heavy use of Ecstasy through most of his twenties and thirties. His neurological problems may be unrelated to his drug use, but it is also possible they represent an idiosyncratic reaction. Β© 2003 Movement Disorder Society
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