Rapidly growing mature teratoma of the mediastinum: Do sex hormones affect growth of the tumor?
✍ Scribed by Tadashi Uyama; Yasumasa Monden; Kunihiko Harada; Suguru Kimura; Tadaoki Morimoto; Kazumasa Miura; Toshikatsu Taniki; Nobuyuki Tanida
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 560 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-4790
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✦ Synopsis
The case of a 12-year-old girl with an anterior mediastinal tumor is reported. A mass grew rapidly and occupied the anterior mediastinum after menarche. Resected material was diagnosed as a mature teratoma. Both estrogen receptors and progesterone receptors were detected in the resected tissue. The titer of estrogen receptors was 2-11.3 femtomoles per milligram of protein and that of progesterone receptors was 9.5-15.7 fmol/mg protein. Based on these data, it was surmised that sex hormones may affect the growth of the tumor in this case. The change in sex hormones after menarche may have played a role in the rapid growth of this tumor.