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Rapid transformation of human fibroblasts with low growth potential into established cell lines by SV40

✍ Scribed by Todaro, George J. ;Wolman, Sandra R. ;Green, Howard

Publisher
Wiley (John Wiley & Sons)
Year
1963
Tongue
English
Weight
903 KB
Volume
62
Category
Article
ISSN
0095-9898

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## Abstract Human skin fibroblasts derived from patients with nephropathic cystinosis were transformed with SV40 virions, cloned and permitted to enter the degenerative stage of growth termed β€œcrisis,” characteristics of SV40 transformed human cells. Nephropathic cystinosis is an autosomal recessiv