Rapid synthesis of substituted 5-phenyl-1,3-dioxolan-4-ones under microwave-induced solvent-free conditions

✍ Scribed by Rochelle R. Ferrett; Michael J. Hyde; Kimberly A. Lahti; Timothy L. Friebe

• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 153 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)00280-6

✦ Synopsis

Under microwave irradiation and without solvent, racemic and optically pure mandelic acid readily condenses with aldehydes and ketones to give 2-alkyl substituted 5-phenyl-1,3-dioxolan-4-ones in good yield.