Rapid stimulation of calcium uptake by isolated rat enterocytes by 1,25(OH)2D3
✍ Scribed by Philip A. Lucas; Chantal Roullet; Patricia Duchambon; Bernard Lacour; Tilman Drüeke
- Book ID
- 104820663
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 838 KB
- Volume
- 413
- Category
- Article
- ISSN
- 0031-6768
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## Abstract Demonstrating 1,25(OH)~2~D~3~‐stimulated calcium uptake in isolated chick intestinal epithelial cells has been complicated by simultaneous enhancement of both uptake and efflux. We now report that in intestinal cells of adult birds, or those of young birds cultured for 72 h, 1,25(OH)~2~
The steroid hormone 1␣,25(OH) 2 -vitamin D 3 (1␣,25(OH) 2 D 3 ) generates biological responses in intestinal and other cells via both genomic and rapid, nongenomic signal transduction pathways. We examined the hypothesis that 1␣,25(OH) 2 D 3 action in chick enterocytes may be linked to pathways invo