Rapid, stability-indicating, high-pressure liquid chromatographic determination of theophylline, guaifenesin, and benzoic acid in liquid and solid pharmaceutical dosage forms

✍ Scribed by D. R. Heidemann

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: English
• Weight: 294 KB
• Volume: 68
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600680443

✦ Synopsis

Theophylline, guaifenesin, and benzoic acid were determined by reversed-phase high-pressure liquid chromatography without interference from active and/or vehicle decomposition. A degradation product of sucrose, 5-hydroxymethylfurfural, can be identified and quantified in liquid samples simultaneously.