Quantitation of SAR97276 in mouse tissue
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Delphine Margout; Sharon Wein; Hermine Gandon; Florence Gattacceca; Henri J. Via
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Article
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2009
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John Wiley and Sons
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English
⚖ 762 KB
## Abstract 1,12‐Bis[5‐(2‐hydroxyethyl)‐4‐methyl‐1,3‐thiazol‐3‐ium]dodecane dibromide (SAR97276, T3) is a new antimalarial drug, which is currently being evaluated in clinical trials for severe malaria. Drug accumulation inside the parasite and a dual mechanism of action are a major strength of thi