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Rapid recurrence of nonalcoholic fatty liver disease after transplantation in a child with hypopituitarism and hepatopulmonary syndrome

✍ Scribed by Maureen M. Jonas; Laura E. Krawczuk; Heung Bae Kim; Craig Lillehei; Antonio Perez-Atayde

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 248 KB
Volume: 11
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.20332

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✦ Synopsis

Nonalcoholic fatty liver disease (NAFLD) has been reported in adults with hypothalamic or pituitary dysfunction, and some have progressed to end stage liver disease requiring transplantation. We report a teenager who initially presented with hypoxia due to intrapulmonary shunting, found to have NAFLD and cirrhosis associated with a hypothalamic tumor and panhypopituitarism. The NAFLD recurred very quickly after a successful liver transplant. Hepatopulmonary syndrome may be more common in cirrhosis associated with pituitary dysfunction than in other types of cirrhosis.

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