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Rapid profiling of bovine and human milk gangliosides by matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry

✍ Scribed by Hyeyoung Lee; Hyun Joo An; Larry A. Lerno Jr.; J. Bruce German; Carlito B. Lebrilla

Book ID: 113652494
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 1005 KB
Volume: 305
Category: Article
ISSN: 1387-3806
DOI: 10.1016/j.ijms.2010.10.020

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## Abstract Posttranslational modifications such as glycosylation can play a fundamental role in signaling pathways that transform an ordinary cell into a malignant one. The development of a protocol to detect these changes in the preliminary stages of disease can lead to a sensitive and specific d