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Rapid micromethod for determination of 15N enrichment in plasma lysine: Application to measurement of whole body protein turnover

✍ Scribed by D.M. Bier; H.L. Christopherson


Book ID
102984347
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
580 KB
Volume
94
Category
Article
ISSN
0003-2697

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✦ Synopsis


A simple, sensitive method, requiring less than 1 ml of blood, is described for measurement of stable isotope enrichment in plasma lysine with a relative precision of better than 20.5% of the observed value. A measurement of whole body protein turnover obtained by this method was virtually identical to values obtained by more tedious macromethods. The speed of the reported procedure allows its application to routine clinical studies which generate a large number of samples.