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Rapid methods for targeted prenatal diagnosis of common chromosome aneuploidies

✍ Scribed by Brigitte H.W. Faas; Vincenzo Cirigliano; The-Hung Bui


Book ID
119367756
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
548 KB
Volume
16
Category
Article
ISSN
1744-165X

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A probe was generated from the YAC clone 831B9 that was suitable for the prenatal detection of trisomy 21using fluorescence in situ hybridization (FISH). This probe was initially tested on a series of 650 unselected amniotic fluid samples prior to the karyotype being available. 630 were correctly id