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Rapid method for automated on-line extraction and fractionation of plasma leukotrienes and 12-hydroxy-5,8,10,14-eicosatetraenoic acids by reversed-phase high-performance liquid chromatography

โœ Scribed by Eldwin L. VanAlstyne; Stephen M. Spaethe


Book ID
107996981
Publisher
Elsevier Science
Year
1992
Weight
662 KB
Volume
579
Category
Article
ISSN
0378-4347

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A high-performance liquid chromatographic system, combining solid-phase extraction and automated precolumn derivatization is described for the routine determination of methotrexate in human plasma. The sample extraction and elution onto the analytical column were performed automatically and concomit