Gd-DTPA kinetics in arterial blood was investigated by dynamic MRI in 47 patients with malignant and benign mammary tumors. Signal enhancement was monitored for 10 min after the beginning of a 1-min infusion of 0.1 mmol/kg Gd-DTPA. Kinetics in blood was biexponential with median half-lives of 21 sec
β¦ LIBER β¦
Rapid Measurement of Capillary Permeability Using the Early Part of the Dynamic Gd-DTPA MRI Enhancement Curve
β Scribed by P.S. Tofts; B.A. Berkowitz
- Book ID
- 102972407
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 632 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1064-1866
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## Abstract We determined the optimum gadolinium (Gd)βDTPA dose and time window for calculating the glomerular filtration rate (GFR) using contrastβenhanced (CE) dynamic MRI and the Patlak plot technique. Twelve adult volunteers with healthy kidneys were included in the study. As a reference method