Defective endothelial nitric oxide synth
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Go Anegawa; Hirofumi Kawanaka; Daisuke Yoshida; Kozo Konishi; Shohei Yamaguchi;
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Article
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2007
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John Wiley and Sons
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English
β 805 KB
In liver cirrhosis, down-regulation of endothelial nitric oxide synthase (eNOS) has been implicated as a cause of increased intrahepatic resistance. We investigated whether Rho-kinase activation is one of the molecular mechanisms involved in defective eNOS signaling in secondary biliary cirrhosis. L