Rapid increase in cytosolic calcium ion concentration mediated by acetylcholine receptors in cultured retinal neurons and Müller cells

Rapid increase of intracellular Ca2+conc

Rapid increase of intracellular Ca2+concentration caused by aminoadipic acid enantiomers in retinal Müller cells and neurons in vitro

✍ Masato Wakakura; Noboru Yamamoto 📂 Article 📅 1992 🏛 Springer-Verlag 🌐 English ⚖ 846 KB

The ability of the gliotoxic compounds D,L-, D-or L-2-aminoadipic acid (AAA) to increase selectively the intracellular concentration of free calcium ion ([CaZ+]~) was examined in Miiller cells cultured with or without retinal neurons. The monitoring of [Ca2+]~ following exposure to 0.06 to 6 mM AAA