Primed in situ labeling (PRINS) is a relatively new technology with wide-ranging applications in clinical cytogenetics. Using PRINS, we have identified the chromosomal origin of marker chromosomes in three patients. In the first patient with primary amenorrhea, we were able to confirm the marker chr
✦ LIBER ✦
Rapid identification and determination of purity of flow-sorted plant chromosomes using C-PRINS
✍ Scribed by Marie Kubaláková; Martin A. Lysák; Jan Vrána; Hana Šimková; Jarmila Číhalíková; Jaroslav Doležel
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 236 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0196-4763
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The breakpoints of deletions and translocations in the proximal chromosome 14q region were defined in nine patients, four of whom have not been reported previously. The aberrant chromosomes were isolated by flow cytometry and used to map the chromosome 14 deletion or translocation breakpoints. The p