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Rapid high-performance liquid chromatographic method for the measurement of the enantiomers of metoprolol in serum using a chiral stationary phase

✍ Scribed by David R. Rutledge; Cindy Garrick


Publisher
Elsevier Science
Year
1989
Weight
668 KB
Volume
497
Category
Article
ISSN
0378-4347

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High performance liquid chromatographic
✍ Uwe Conrad; Bezhan Chankvetadze; Gerhard K. E. Scriba πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 526 KB

## Abstract A chiral stationary phase (CSP) based on (–)‐(18‐crown‐6)‐2,3,11,12‐tetracarboxylic acid was evaluated for the direct resolution of the enantiomers of dipeptides and tripeptides. The type and concentration of the acid and the methanol content were optimized with regard to retention time