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Rapid genotyping of MBL2 gene mutations using real-time PCR with fluorescent hybridisation probes

✍ Scribed by R Steffensen; K Hoffmann; K Varming

Book ID: 114051353
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 700 KB
Volume: 278
Category: Article
ISSN: 0022-1759
DOI: 10.1016/s0022-1759(03)00190-x

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## Abstract The UGT1A1 Taqman MGB probe single nucleotide polymorphism (SNP) genotyping assay was developed to detect nucleotide 211 of the UDP‐glucoronocyltransferase 1A1 (UGT1A1) gene. Defects in this enzyme interfere with process of conjugation of bilirubin and cause unconjugated hyperbilirubine