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RAPID FETAL SEX DETERMINATION IN FIRST TRIMESTER PRENATAL DIAGNOSIS BY DOT HYBRIDISATION OF DNA PROBES

✍ Scribed by Gosden, J.R; Christie, S; Gosden, C.M; Morsman, J.M; Rodeck, C.H


Book ID
123602916
Publisher
The Lancet
Year
1984
Tongue
English
Weight
333 KB
Volume
323
Category
Article
ISSN
0140-6736

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The close genetic linkage between the gene for congenital adrenal hyperplasia due to 21-hydroxylase (21-OH) deficiency and HLA genes allowed us to use the polymorphism of this system as a marker of the disease. HLA genotyping can be performed by using restriction enzyme fragments hybridized with spe