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Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors

✍ Scribed by Rothenburg, Stefan; Seo, Eun Joo; Gibbs, James S; Dever, Thomas E; Dittmar, Katharina

Book ID
109965619
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
891 KB
Volume
16
Category
Article
ISSN
1545-9993

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## Abstract Raf kinase inhibitory protein (RKIP) is a metastasis suppressor whose expression is reduced in nasopharyngeal carcinoma (NPC) tissues and is absent in NPC metastases. To investigate the effect of RKIP on radiosensitivity of NPC, high metastatic 5‐8F with low RKIP expression and non‐meta