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Rapid evolution of cancer/testis genes on the X chromosome

โœ Scribed by Brian J Stevenson; Christian Iseli; Sumir Panji; Monique Zahn-Zabal; Winston Hide; Lloyd J Old; Andrew J Simpson; C Victor Jongeneel


Book ID
111912678
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
332 KB
Volume
8
Category
Article
ISSN
1471-2164

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## Abstract Cancer/testis (CT) genes are normally expressed in germ cells only, yet are reactivated and expressed in some tumors. Of the approximately 40 CT genes or gene families identified to date, 20 are on the X chromosome and are present as multigene families, many with highly conserved member