Rapid development of ganciclovir-resistant cytomegalovirus infection in children after allogeneic stem cell transplantation in the early phase of immune cell recovery
✍ Scribed by Eckle, T; Lang, P; Prix, L; Jahn, G; Klingebiel, T; Handgretinger, R; Selle, B; Niethammer, D; Hamprecht, K
- Book ID
- 110013392
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 126 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0007-1188
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The kinetics of the gB-specific and neutralizing antibody responses to human cytomegalovirus (HCMV) were analyzed in 26 allogeneic stem-cell transplant recipients who either did (n = 20) or did not (n = 6) develop asymptomatic HCMV active infection during the study period. Antibody response profiles
## Abstract Addition of in vivo alemtuzumab to the conditioning regimen enabled 2‐ or 3‐locus‐mismatched hematopoietic stem cell transplantation with an acceptable incidence of graft‐versus‐host‐disease. However, the procedure was associated with a high incidence of cytomegalovirus (CMV) reactivati