Rapid detection of illicit drugs in neat saliva using desorption/ionization on porous silicon

Effective detection of peptides containi

Effective detection of peptides containing cysteine sulfonic acid using matrix-assisted laser desorption/ionization and laser desorption/ionization on porous silicon mass spectrometry

✍ Tomoya Kinumi; Yukiyasu Shimomae; Ryuichi Arakawa; Yoshiro Tatsu; Yasushi Shiger 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB

## Abstract Cysteine sulfonic acid‐containing peptides, being typical acidic peptides, exhibit low response in matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry. In this study, matrix conditions and the effect of diammonium hydrogencitrate (DAHC) as additive were investigated fo