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Rapid decrease in N-hydroxy-2-acetylaminofluorene sulfotransferase activity of liver cytosols from rats fed carcinogen

✍ Scribed by David P. Ringer; Kit Kampschmidt; Robert L. King Jr.; Stuart Jackson; Donald E. Kizer

Book ID
115777184
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
515 KB
Volume
32
Category
Article
ISSN
0006-2952

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## Abstract Enzymatic and immunohistochemical experiments were conducted to evaluate the mechanistic basis for the downregulation of the important detoxication/bioactivation enzyme aryl sulfotransferase IV (AST IV) during 2‐ acetylaminofluorene (2AAF)–induced hepatocarcinogenesis. To distinguish be