Rapid cardiac-output measurement with ungated spiral phase contrast

✍ Scribed by Jong B. Park; Bob S. Hu; Steven M. Conolly; Krishna S. Nayak; Dwight G. Nishimura

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 619 KB
• Volume: 56
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.20970

✦ Synopsis

Abstract

An ungated spiral phase‐contrast (USPC) method was used to measure cardiac output (CO) rapidly and conveniently. The USPC method, which was originally designed for small peripheral vessels, was modified to assess CO by measuring flow in the ascending aorta (AA). The modified USPC used a 12‐interleaf spiral trajectory to acquire full‐image data every 283 ms with 2‐mm spatial resolution. The total scan time was 5 s. For comparison, a triggered real‐time (TRT) method was used to indirectly calculate CO by measuring left‐ventricular (LV) volume. The USPC and TRT measurements from all normal volunteers agreed. In a patient with patent ductus arteriosus (PDA), high CO was measured with USPC, which agreed well with the invasive cardiac‐catheterized measurement. In normal volunteers, CO dropped about 20–30% with Valsalva maneuvering, and increased about 100% after exercise. Continuous 28‐s cycling between Valsalva maneuvering and free‐breathing showed that USPC can temporally resolve physiological CO changes. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.