Rapid-bolus contrast-enhanced dynamic computed tomography in acute pancreatitis: A prospective study

✍ Scribed by Mr N. J. M. London; T. Leese; D. F. L. Watkin; D. P. Fossard; J. M. Lavelle; K. Miles; K. P. West

• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 701 KB
• Volume: 78
• Category: Article
• ISSN: 0007-1323
• DOI: 10.1002/bjs.1800781216

✦ Synopsis

and it has been shown that surgeons cannot adequately distinguish necrotic pancreas from necrotic peripancreatic fatI4. However, rapid-bolus contrast-enhanced dynamic computed tomography (CT) can demonstrate areas of reduced perfusion in acute pan~reatitis'~-'', and reduced enhancement correlates well with pancreatic necrosis".

This study was designed to determine the incidence, clinical outcome and pathological significance of CT necrosis in patients with biochemically predicted severe acute pancreatitis.

1. Modified Imrie prognostic score > 3 within 48 h. (Imrie prognostic criteria: age > 5 5 years; white cell count > 15 x 109/l; urea > 16 mmol/l; glucose > 10 mmol/l; albumin <32 g/l; calcium < 2.0 mmol/l; Pa0, < 8 kPa; lactate dehydrogenase > 600 units/l.) 2. C-reactive protein > 0 1 5 g/l at 72 h. 3. White cell count 15 x 109/1 at 7 days.