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Rapid and transient induction of c-fos, c-myc and c-Ha-ras in rat liver following glycine administration

✍ Scribed by S. Vasudevan; G. Lee; P.M. Rao; S. Rajalakshmi; D.S.R. Sarma


Book ID
117058186
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
427 KB
Volume
152
Category
Article
ISSN
0006-291X

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## Abstract Furan administered by gavage for 2 yr has been reported to induce hepatocellular carcinomas in male and female B6C3F~1~ mice and in male but not female F344 rats. Chronic exposure studies in our laboratory using bioassay conditions showed extensive hepatocellular toxicity and sustained