We describe the coupling of a microfabricated fluidic device to an electrospray ionization (ESI) quadrupole time-of-flight mass spectrometer (QqTOFMS) for the identification of protein samples. The microfabricated devices consisted of three reservoirs connected via channels to a main capillary, whic
β¦ LIBER β¦
Rapid and sensitive separation of trace level protein digests using microfabricated devices coupled to a quadrupole - time-of-flight mass spectrometer
β Scribed by Jianjun Li; Can Wang; John F. Kelly; D. Jed Harrison; Pierre Thibault
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 337 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0173-0835
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The combination of a quadrupole orthogonal time-of-flight (Q-TOF) mass spectrometer with fast chromatography has been studied. It was found that the combination was capable of giving good accuracy of mass measurement for mass spectra with errors generally better than 5 ppm. In addition it was shown