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Rapid and sensitive RP-LC method with amperometric detection for pharmacokinetic assessment of propafenone in human serum of healthy volunteers

✍ Scribed by A. Chmielewska; L. Konieczna; A. Plenis; T. Bączek; H. Lamparczyk


Book ID
110212547
Publisher
SP MAIK Nauka/Interperiodica
Year
2010
Tongue
English
Weight
191 KB
Volume
65
Category
Article
ISSN
1061-9348

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## Abstract A highly sensitive and specific LC‐MS/MS method has been developed and validated for the estimation of doxofylline (DFL) with 300 µL human serum using imipramine as the internal standard (IS). The API‐3000 LC‐MS/MS was operated under multiple reaction‐monitoring mode using the electrosp