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Rapid and sensitive determination of morphine in street opium samples by thermal desorption gas chromatography using a microfurnace pyrolyzer

✍ Scribed by Minemasa Hida; Toshiyuki Mitsui; Shin Tsuge; Hajime Ohtani


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
198 KB
Volume
27
Category
Article
ISSN
1615-9306

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✦ Synopsis


Abstract

Thermal desorption of the alkaloids in opium samples at 300°C using a vertical microfurnace pyrolyzer was followed by their on‐line gas chromatographic (GC) analysis on a large‐bore glass capillary column. This method permitted rapid and sensitive determination of the content of the main alkaloid, morphine, in the small (ca. 100 μg) opium samples with a relative standard deviation within 4% for 5 runs. The observed morphine contents of about 12 to 15 w/w% in the given opium samples were in fairly good agreement with those estimated by a conventional GC‐MS method.