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Rapid and sensitive detection of point mutation by DNA ligase-based electrochemiluminescence assay

โœ Scribed by Huijuan Zhou; Da Xing; Debin Zhu; Xiaoming Zhou

Book ID
116903576
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
543 KB
Volume
78
Category
Article
ISSN
0039-9140

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## Abstract The present study reports a proofโ€ofโ€principle for a sensitive genotyping assay approach that can detect single nucleotide polymorphisms (SNPs) based on fluorescence anisotropy measurements through a coreโ€“shell fluorescent nanoparticles assembly and ligase reaction. By incorporating the