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Rapid and efficient ATM mutation detection by fluorescent chemical cleavage of mismatch: identification of four novel mutations

โœ Scribed by Izatt, Louise; Vessey, Carina; Hodgson, Shirley V; Solomon, Ellen


Book ID
110024796
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
418 KB
Volume
7
Category
Article
ISSN
1018-4813

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## Communicated by Mark H. Paalman Mutations in the tumor-suppressor p53 gene TP53 are frequent in most human cancers including breast cancer. A new solid phase chemical cleavage of mismatch method (CCM) allowed rapid and efficient screening and analysis of the TP53 gene in DNA samples extracted