Rapid and cost effective screening of breast and ovarian cancer genes using novel sequence capture method in clinical samples

Novel TP53 gene mutations in tumors of R

Novel TP53 gene mutations in tumors of Russian patients with breast cancer detected using a new solid phase chemical cleavage of mismatch method and identified by sequencing

✍ A. Lambrinakos; M. Yakubovskaya; J.J. Babon; A.A. Neschastnova; Ya.V. Vishnevska 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 281 KB 👁 2 views

## Communicated by Mark H. Paalman Mutations in the tumor-suppressor p53 gene TP53 are frequent in most human cancers including breast cancer. A new solid phase chemical cleavage of mismatch method (CCM) allowed rapid and efficient screening and analysis of the TP53 gene in DNA samples extracted