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Randomized trial of pramipexole for patients with restless legs syndrome (RLS) and RLS-related impairment of mood

✍ Scribed by Pasquale Montagna; Magdolna Hornyak; Jan Ulfberg; Seung Bong Hong; Juergen Koester; Giovanna Crespi; Stefan Albrecht

Book ID
116884970
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
288 KB
Volume
12
Category
Article
ISSN
1389-9457

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## Abstract We evaluated the efficacy of pramipexole versus placebo in restless legs syndrome (RLS) for 6 weeks. Overall, 345 patients were randomly assigned in a 1:2 ratio to receive either placebo (n = 115) or pramipexole (n = 230) with a starting dose of 0.125 mg/day. The dose was individually o