Randomized trial of cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil with node-positive breast cancer in Japan
β Scribed by Morihiko Kimura; Takeshi Tominaga; Yuichi Takatsuka; Masakazu Toi; Rikiya Abe; Hiroki Koyama; Shigemitsu Takashima; Yasuo Nomura; Shigeto Miura; Izo Kimijima; Hideya Tashiro; Yasuo Ohashi; Adjuvant CEF Research Group for Breast Cancer
- Book ID
- 107643758
- Publisher
- Springer Japan
- Year
- 2009
- Tongue
- English
- Weight
- 224 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1340-6868
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## Abstract ## BACKGROUND According to the overview of Early Breast Cancer Trialists' Collaborative Group, anthracycline containing regimens are superior to cyclophosphamide, methotrexate, and 5βfluorouracil (CMF) as adjuvant chemotherapy for breast carcinoma, but no comparative information is ava
Twenty-nine patients with metastatic breast cancer were treated with fluorouracil, adriamycin, cyclophosphamide (FAC), and methotrexate (MTX), with or without leukovorin rescue. Of 24 evaluable patients, one achieved a complete remission and 17 had partial responses. The overall objective response r