## Abstract A lack of antiviral response in patients with chronic hepatitis C treated with pegylated (PEG)‐interferon (IFN)‐α‐2a + ribavirin (RIBA) may be explained by neutralizing antibodies to IFN‐α‐2a. The aim of this study was to assess neutralizing antibodies to IFN‐α‐2a and IFN levels in non‐
Randomized trial comparing pegylated interferon α-2b versus pegylated interferon α-2a, both plus ribavirin, to treat chronic hepatitis C in human immunodeficiency virus patients
✍ Scribed by Montserrat Laguno; Carmen Cifuentes; Javier Murillas; Sergio Veloso; Maria Larrousse; Antoni Payeras; Lucia Bonet; Francese Vidal; Ana Milinkovic; Antoni Bassa; Concha Villalonga; Iñaki Pérez; Cristina Tural; Maria Martínez-Rebollar; Marta Calvo; Jose Luis Blanco; Estaban Martínez; Jose M. Sánchez-Tapias; Jose M. Gatell; Jose Mallolas
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 370 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0270-9139
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📜 SIMILAR VOLUMES
Combination treatment with pegylated-interferon-alpha (PEG IFN-␣) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection, results in a sustained virological response (SVR) in only about half of patients. Because genes involved in the interferon-alpha pathway may
## Abstract The aim of this study was to compare the efficacy of high‐dose interferon (IFN)‐α‐2b with standard dose of IFN‐α‐2b in combination with ribavirin (RBV) for patients with chronic hepatitis C virus (HCV) infection, and to investigate the predictive factors associated with virological resp