Randomized equivalence trials: The example of the 6th wilm's tumor study of the international society of pediatric oncology (SIOP)
✍ Scribed by Com-Nougué, C; Tournade, MF; Rodary, C; de Kraker, J; Voûte, T; Lemerle, J
- Book ID
- 122402531
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 164 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0959-8049
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This descriptive epidemiology study of 1,040 children with Wilms' tumor (WT) registered in the International Society of Paediatric Oncology (SIOP) clinical trials confirms the findings reported by the National Wilms' Tumor Study. The male:female rate was 0.89:l. The mean age at diagnosis of the 43 b
## Abstract For decades radiation has generally been accepted as a valuable supplement to surgery in the treatment of Wilms' tumor; unfortunately, it may produce undesirable late effects. It turned out, however, that when treatment is adjusted to known variables, the risk for late sequelae can be d
Background. Unlike the original definitions of focal (FA) and diffuse anaplasia (DA) in Wilms tumor (WT), recently redefined FA and DA proved to be of prognostic significance. The aim of the study was to analyze WT from the SIOP file, the majority of which were treated with preoperative chemotherapy