𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Randomized, double-blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease

✍ Scribed by Yoshikuni Mizuno; Nobuo Yanagisawa; Sadako Kuno; Mitsutoshi Yamamoto; Kazuko Hasegawa; Hideki Origasa; Hisayuki Kowa


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
103 KB
Volume
18
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

We compared the efficacy and safety of pramipexole (PPX) with placebo in the treatment of advanced Parkinson's disease (PD) as an adjunct to levodopa. A bromocriptine (BR) group was included to enable determination of the noninferiority of PPX relative to BR as the standard treatment. Β© 2003 Movement Disorder Society


πŸ“œ SIMILAR VOLUMES


Randomized, double-blind, multicenter ev
✍ Robert A. Hauser; Anthony H.V. Schapira; Olivier Rascol; Paolo Barone; Yoshikuni πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 220 KB πŸ‘ 1 views

## Abstract The objective of this study was to evaluate the efficacy and safety of pramipexole extended release (ER) administered once daily in early Parkinson's disease (PD). Pramipexole immediate release (IR) administered three times daily (TID) is an efficacious and generally well‐tolerated trea

Rotigotine transdermal patch in early Pa
✍ Nir Giladi; Babak Boroojerdi; Amos D. Korczyn; David J. Burn; Carl E. Clarke; An πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 167 KB

## Abstract Rotigotine is a new, non‐ergot dopamine agonist formulated in a transdermal delivery system. The present study was to investigate the efficacy and safety of the rotigotine transdermal patch in the treatment of early Parkinson's disease. Patients (n = 561) were randomized to rotigotine,

Botulinum toxin type A for drooling in P
✍ Giovanni Lagalla; Marzia Millevolte; Marianna Capecci; Leandro Provinciali; Mari πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 65 KB

To investigate the safety and efficacy of botulinum toxin type A (BoNTX) treatment to reduce sialorrhea in Parkinson's disease (PD), a double-blind, randomized, placebo-controlled study enrolled 32 PD patients complaining of excessive drooling. Patients received either 50 U Botox in each parotid gla

Comparison of desipramine and citalopram
✍ David Devos; Kathy Dujardin; Isabelle Poirot; Caroline Moreau; Olivier Cottencin πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 118 KB πŸ‘ 2 views

## Abstract Depression is one of the most common psychiatric disturbances in Parkinson's disease (PD). Recent reviews have highlighted the lack of controlled trials and the ensuing difficulty in formulating recommendations for antidepressant use in PD. We sought to establish whether antidepressants

Safety and efficacy of perampanel in adv
✍ Karla Eggert; David Squillacote; Paolo Barone; Richard Dodel; Regina Katzenschla πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 117 KB πŸ‘ 1 views

Squillacote, received compensation from Eisai for their site's conduct of the study. Drs. Barone, Lees, and Oertel received honoraria from Eisai as members of the Advisory Board of this study. Dr. Rascol has received unrestricted scientific grant and honoraria from Eisai for his advice to the compan

A double-blind randomized crossover tria
✍ Dr. Arthur S. Walters; Wayne A. Hening; Neil Kavey; Sudhansu Chokroverty; Steve πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 419 KB πŸ‘ 2 views

A double-blind randomized crossover study of 7.5 mg bromocriptine at bedtime versus placebo was conducted in 30-day phases (with a 2-week washout period between phases) in 6 patients with idiopathic restless legs syndrome. Five patients experienced partial subjective improvement in restlessness and