Chronic hepatitis C is often a progressive liver disease for which there is no satisfactory treatment. We studied the efficacy of recombinant a-interferon or y-interferon in the treatment of this disease in comparison with a control group. Thirty patients were randomly assigned to three groups. Ten
Randomized controlled trial of recombinant alpha-2a-interferon for chronic hepatitis C
โ Scribed by David D. Douglas; Jorge Rakela; Hsiang Ju Lin; F. Blaine Hollinger; Howard F. Taswell; Albert J. Czaja; John B. Gross; Monte L. Anderson; Kevin Parent; C. Richard Fleming; John R. Cangemi; Peter C. O'Brien; Pauline E. Powis
- Book ID
- 112515334
- Publisher
- Springer US
- Year
- 1993
- Tongue
- English
- Weight
- 653 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0163-2116
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Sixty consecutive patients with chronic hepatitis C were included in a randomized controlled trial of recombinant human interferon-%, vs. no treatment. Treated patients received tapering doses of interferon thrice weekly for 1 yr. Twenty treated cases (66.7%) normalized serum aminotransferase levels
AND THE CONSENSUS INTERFERON STUDY GROUP 15 tion. Efficacy was assessed by normalization of serum alanine This multicenter, randomized, controlled, double-blind, transaminase (ALT) concentration and decrease in serum hepphase III study in 704 patients with chronic hepatitis C infecatitis C virus (HC