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Randomised trial of pyronaridine versus chloroquine for acute uncomplicated falciparum malaria in Africa

✍ Scribed by P Ringwald; J Bickii; P Ringwald; L Basco; L Basco

Book ID: 118562008
Publisher: The Lancet
Year: 1996
Tongue: English
Weight: 765 KB
Volume: 347
Category: Article
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(96)91558-5

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Chlorpheniramine, a histamine HI receptor antagonist, reverses chloroquine resistance in Plasmodium falciaarum in vitro. However. the clinical sianificance of this remains unclear. We have evaluated the efficacv of chloroquine and a chloroquine-chlorbheniramine combination in 112 consecutive childre