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Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies

โœ Scribed by Buhm Han; Eleazar Eskin


Book ID
113423037
Publisher
American Society of Human Genetics
Year
2011
Tongue
English
Weight
668 KB
Volume
88
Category
Article
ISSN
0002-9297

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In genome-wide association studies (GWAS), it is a common practice to impute the genotypes of untyped single nucleotide polymorphism (SNP) by exploiting the linkage disequilibrium structure among SNPs. The use of imputed genotypes improves genome coverage and makes it possible to perform meta-analys