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Random aneuploidy in CML patients at diagnosis and under imatinib treatment

✍ Scribed by A. Amiel; M. Yukla; E. Gaber; L. Leopold; G. Josef; M. Fejgin; M. Lishner


Book ID
113512909
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
91 KB
Volume
168
Category
Article
ISSN
0165-4608

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## Abstract Imatinib (IM) is considered the gold standard for chronic myeloid leukemia (CML) treatment, although resistance is emerging as a significant problem. The proinflammatory cytokines interleukin‐6 (IL‐6) and interleukin‐8 (IL‐8) play an important role in cell proliferation, survival, and r