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Random and cyclical deletion of large DNA segments in the genome of Pseudomonas putida

✍ Scribed by Audrey Leprince; Víctor de Lorenzo; Petra Völler; Mark W. J. van Passel; Vitor A. P. Martins dos Santos

Book ID
115184462
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
941 KB
Volume
14
Category
Article
ISSN
1462-2912

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While methods for the detection of point mutations and small insertions or deletions in genomic DNA are well established, the detection of larger (>100 bp) genomic duplications or deletions can be more difficult. Most mutation scanning methods use PCR as a first step, but the subsequent analyses are